Wegovy

Wegovy is a once-weekly injectable medication containing the active ingredient semaglutide, a GLP-1 receptor agonist. It mimics a natural hormone (glucagon-like peptide-1) that regulates appetite and food intake.

• Brand name: Wegovy

• Generic name: Semaglutide

• Drug class: GLP-1 receptor agonist

• Manufacturer: Novo Nordisk

• FDA approval: June 2021 (for chronic weight management)

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Approved Uses

Wegovy is approved for:

1. Adults with:

   • Obesity (BMI ≥30), or

   • Overweight (BMI ≥27) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol

2. Adolescents (12–17 years) with:

   • Obesity (BMI ≥95th percentile for age and sex)

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How Wegovy Works

Semaglutide mimics GLP-1, a natural hormone that:

• Increases insulin secretion (in response to food)

• Delays stomach emptying, helping you feel full longer

• Acts on the brain to reduce appetite and cravings

Together, this leads to reduced calorie intake and weight loss.